Syndetics cover image
Image from Syndetics

Molecular Imaging in Oncology [electronic resource].

By: Contributor(s): Material type: Computer fileComputer filePublisher number: 9783642108525Series: Recent Results in Cancer ResearchPublication details: Dordrecht : Springer, 2011.ISBN:
  • 9783642108532
Subject(s): Genre/Form: Additional physical formats: Print version:: Molecular Imaging in OncologyDDC classification:
  • 616.99/40754 616.9940754
LOC classification:
  • RC270.3 .D53
Online resources:
Contents:
Molecular Imagingin Oncology; Preface; Contents; Part I Technology and Probe Design; 1 Computed Tomography and Magnetic Resonance Imaging; Abstract; 1...Imaging Targets in Cancer; 1.1 Introduction; 1.2 Physiological Imaging Targets; 1.3 Molecular Targets; 1.4 Cellular Targets; 1.5 Image-Guided Drug Delivery; 2...Recent Technological Developments in X-ray Computed Tomography of Cancer; 2.1 Basics of Multi-Slice Spiral Computed Tomography; 2.1.1 Brief History; 2.1.2 Data Acquisition; 2.1.3 Image Reconstruction; 2.1.4 Radiation Dose; 2.2 Multi-Energy Computed Tomography
2.3 Preclinical Computed Tomography2.4 Dedicated Imaging Systems and New Developments; 2.5 Multimodality Imaging; 3...Recent Technological Developments in Magnetic Resonance Imaging of Cancer; 3.1 Magnetic Resonance Imaging: Introduction; 3.2 MRI Signal Formation and Contrast; 3.3 Magnetic Field Strength and Signal Sensitivity; 3.4 Imaging Gradients, Signal Encoding, and Signal Reception Chain; 3.5 MRI Pulse Sequences, Parametric Mapping; 3.6 Contrast-Enhanced MRI; 4...Imaging Biomarkers in Cancer; 4.1 Imaging Biomarkers: X-ray Computed Tomography
3.1 Somatostatin Analogs3.2 Bombesin Analogs; 3.3 Neurotensin Analogs; 3.4 Other Peptides-Based Radiotracers; 4...Antibodies and Antibody Fragments; 4.1 Targeting Fibronectin Extra-Domain B: Antiangiogenic Antibody Fragment L19; 5...Vitamin-Based Radiotracers; 5.1 Folic Acid Conjugates; 5.2 Vitamin B12 Conjugates; 5.3 Other Vitamin Targeting Agents; 6...Intracellular Targets; 6.1 99mTc-Carbohydrate Complexes; 6.2 Radiolabeled Nucleoside Analogs for Targeting Human Thymidine Kinase; 6.3 Radioiodinated Meta-Iodobenzylguanidine; 7...Optimization of SPECT Tracer Design and Potential Reasons for Failure
4.2 Imaging Biomarkers: Magnetic Resonance Imaging4.2.1 Angiography and Angiogenesis (MRA); 4.2.2 Perfusion (DCE MRI); 4.2.3 Blood Oxygenation Level-Dependent Imaging; 4.2.4 Diffusion Weighted Imaging; 4.2.5 Intracellular and Extracellular Sodium Concentrations; 4.2.6 Metabolite Concentration Using MRS; 4.2.7 Extracellular pH and Hypoxia; 5...Magnetic Resonance Imaging Probes in Cancer; 5.1 Introduction; 5.2 Non-Targeted Probes; 5.2.1 Low Molecular Weight Agents; 5.2.2 High Molecular Weight Agents; 5.2.3 Protein-Based MR Agents; 5.2.4 Lipid-Based Nanoparticles; 5.2.5 Dendrimers
5.2.6 Linear Polymers (Polylysine, PEG, and Polysaccharide Complexes)5.2.7 Iron Oxides; 5.2.8 Gadofullerenes and Gadonanotubes; 5.3 Targeted Probes; 5.4 Responsive Probes; 5.5 Reporter Genes; 5.5.1 Transferrin Receptor Reporter Gene; 5.5.2 Ferritin Reporter Gene; 5.5.3 Tyrosinase MR Reporter Gene; 5.5.4 beta -Galactosidase and MagA Reporter Gene; 5.5.5 Alternate Approaches; 6...Future Perspectives; References; 2 Single Photon Emission Computed Tomography Tracer; Abstract; 1...Introduction; 2...General Aspects for the Design of SPECT Tracers; 3...Peptide-Receptor Radionuclide Imaging
8...Summary and Conclusion
Summary: The impact of molecular imaging on diagnostics, therapy, and follow-up in oncology is increasing steadily. Many innovative molecular imaging probes have already entered clinical practice, and there is no doubt that the future emphasis will be on multimodality imaging in which morphological, functional, and molecular imaging techniques are combined in a single clinical investigation. This handbook addresses all aspects of molecular imaging in oncology, from basic research to clinical applications. The first section is devoted to technology and probe design, and examines a variety of PET and SPE
Holdings
Item type Home library Call number Status Date due Barcode Item holds
Electronic Resource Electronic Resource UH Online Library Ebooks Not for loan
Total holds: 0

Enhanced descriptions from Syndetics:

Description based upon print version of record.

Molecular Imagingin Oncology; Preface; Contents; Part I Technology and Probe Design; 1 Computed Tomography and Magnetic Resonance Imaging; Abstract; 1...Imaging Targets in Cancer; 1.1 Introduction; 1.2 Physiological Imaging Targets; 1.3 Molecular Targets; 1.4 Cellular Targets; 1.5 Image-Guided Drug Delivery; 2...Recent Technological Developments in X-ray Computed Tomography of Cancer; 2.1 Basics of Multi-Slice Spiral Computed Tomography; 2.1.1 Brief History; 2.1.2 Data Acquisition; 2.1.3 Image Reconstruction; 2.1.4 Radiation Dose; 2.2 Multi-Energy Computed Tomography

2.3 Preclinical Computed Tomography2.4 Dedicated Imaging Systems and New Developments; 2.5 Multimodality Imaging; 3...Recent Technological Developments in Magnetic Resonance Imaging of Cancer; 3.1 Magnetic Resonance Imaging: Introduction; 3.2 MRI Signal Formation and Contrast; 3.3 Magnetic Field Strength and Signal Sensitivity; 3.4 Imaging Gradients, Signal Encoding, and Signal Reception Chain; 3.5 MRI Pulse Sequences, Parametric Mapping; 3.6 Contrast-Enhanced MRI; 4...Imaging Biomarkers in Cancer; 4.1 Imaging Biomarkers: X-ray Computed Tomography

3.1 Somatostatin Analogs3.2 Bombesin Analogs; 3.3 Neurotensin Analogs; 3.4 Other Peptides-Based Radiotracers; 4...Antibodies and Antibody Fragments; 4.1 Targeting Fibronectin Extra-Domain B: Antiangiogenic Antibody Fragment L19; 5...Vitamin-Based Radiotracers; 5.1 Folic Acid Conjugates; 5.2 Vitamin B12 Conjugates; 5.3 Other Vitamin Targeting Agents; 6...Intracellular Targets; 6.1 99mTc-Carbohydrate Complexes; 6.2 Radiolabeled Nucleoside Analogs for Targeting Human Thymidine Kinase; 6.3 Radioiodinated Meta-Iodobenzylguanidine; 7...Optimization of SPECT Tracer Design and Potential Reasons for Failure

4.2 Imaging Biomarkers: Magnetic Resonance Imaging4.2.1 Angiography and Angiogenesis (MRA); 4.2.2 Perfusion (DCE MRI); 4.2.3 Blood Oxygenation Level-Dependent Imaging; 4.2.4 Diffusion Weighted Imaging; 4.2.5 Intracellular and Extracellular Sodium Concentrations; 4.2.6 Metabolite Concentration Using MRS; 4.2.7 Extracellular pH and Hypoxia; 5...Magnetic Resonance Imaging Probes in Cancer; 5.1 Introduction; 5.2 Non-Targeted Probes; 5.2.1 Low Molecular Weight Agents; 5.2.2 High Molecular Weight Agents; 5.2.3 Protein-Based MR Agents; 5.2.4 Lipid-Based Nanoparticles; 5.2.5 Dendrimers

5.2.6 Linear Polymers (Polylysine, PEG, and Polysaccharide Complexes)5.2.7 Iron Oxides; 5.2.8 Gadofullerenes and Gadonanotubes; 5.3 Targeted Probes; 5.4 Responsive Probes; 5.5 Reporter Genes; 5.5.1 Transferrin Receptor Reporter Gene; 5.5.2 Ferritin Reporter Gene; 5.5.3 Tyrosinase MR Reporter Gene; 5.5.4 beta -Galactosidase and MagA Reporter Gene; 5.5.5 Alternate Approaches; 6...Future Perspectives; References; 2 Single Photon Emission Computed Tomography Tracer; Abstract; 1...Introduction; 2...General Aspects for the Design of SPECT Tracers; 3...Peptide-Receptor Radionuclide Imaging

8...Summary and Conclusion

The impact of molecular imaging on diagnostics, therapy, and follow-up in oncology is increasing steadily. Many innovative molecular imaging probes have already entered clinical practice, and there is no doubt that the future emphasis will be on multimodality imaging in which morphological, functional, and molecular imaging techniques are combined in a single clinical investigation. This handbook addresses all aspects of molecular imaging in oncology, from basic research to clinical applications. The first section is devoted to technology and probe design, and examines a variety of PET and SPE