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Lecture notes on molecular medicine / John Bradley, David Rubenstein, David Johnson.

By: Contributor(s): Material type: TextTextSeries: Lecture notes (Cavendish Publishing Limited)Publication details: Oxford : Blackwell Science, c1995.ISBN:
  • 0632038519
  • 0632038535
Subject(s): DDC classification:
  • 616.042 20
Contents:
1. Basic principles. DNA. RNA structure. DNA replication and transcription: it's all in the genes. Gene expression: making proteins. Gene transcription: transmitting the code. Translation: reading the code -- 2. Manipulation of DNA/RNA. Preparation of nucleic acid. Cutting and pasting DNA (restriction enzymes and ligases). Extending and chewing DNA (polymerases and nucleases). Making RNA from DNA and vice versa: RNA Pol and reverse transcriptase -- 3. Molecular techniques. Blotting. Hybridization. Transfection and transformation: selection and screening. DNA analysis. RNA analysis. Nucleic acid-protein interactions. Transgenic animals (adding genes). Knockout animals (deleting genes) -- 4. Understanding genetics. Evolution of the human genome. Inheriting genes. Diversity in the genome: why are we different? Identifying genetic differences between individuals. Finding genes -- 5. Molecular medicine in practice. Biotechnology in clinical medicine.
Summary: Lecture Notes on Molecular Medicine is a core text that aims to give a concise and clear introduction to how molecular biology works, and how it is used to understand and treat human disease. There are five major sections: basic principles outlines the fundamentals of DNA structure and function, gene structure and expression; manipulation of DNA/RNA introduces the concepts of cutting, separating and transferring genetic material between cells; molecular techniques covers the essential practical aspects of molecular biology that underpin molecular medicine; understanding genetics revises the basics of medical genetics in order to identify the areas to which molecular biology can and has been applied; and molecular medicine in practice describes the discoveries and insights that the application of molecular biology has produced. Lecture Notes on Molecular Medicine will appeal to a wide ranging audience, from medical students to higher examination candidates, who want a straightforward introduction to one of the most important growth areas in modern medicine.
Holdings
Item type Home library Call number Status Date due Barcode Item holds
Two Week Loan Two Week Loan College Lane Learning Resources Centre Main Shelves 616.042 BRA (Browse shelf(Opens below)) Available 4403858305
Two Week Loan Two Week Loan College Lane Learning Resources Centre Main Shelves 616.042 BRA (Browse shelf(Opens below)) Available 4403892796
Total holds: 0

Enhanced descriptions from Syndetics:

Includes index.

1. Basic principles. DNA. RNA structure. DNA replication and transcription: it's all in the genes. Gene expression: making proteins. Gene transcription: transmitting the code. Translation: reading the code -- 2. Manipulation of DNA/RNA. Preparation of nucleic acid. Cutting and pasting DNA (restriction enzymes and ligases). Extending and chewing DNA (polymerases and nucleases). Making RNA from DNA and vice versa: RNA Pol and reverse transcriptase -- 3. Molecular techniques. Blotting. Hybridization. Transfection and transformation: selection and screening. DNA analysis. RNA analysis. Nucleic acid-protein interactions. Transgenic animals (adding genes). Knockout animals (deleting genes) -- 4. Understanding genetics. Evolution of the human genome. Inheriting genes. Diversity in the genome: why are we different? Identifying genetic differences between individuals. Finding genes -- 5. Molecular medicine in practice. Biotechnology in clinical medicine.

Lecture Notes on Molecular Medicine is a core text that aims to give a concise and clear introduction to how molecular biology works, and how it is used to understand and treat human disease. There are five major sections: basic principles outlines the fundamentals of DNA structure and function, gene structure and expression; manipulation of DNA/RNA introduces the concepts of cutting, separating and transferring genetic material between cells; molecular techniques covers the essential practical aspects of molecular biology that underpin molecular medicine; understanding genetics revises the basics of medical genetics in order to identify the areas to which molecular biology can and has been applied; and molecular medicine in practice describes the discoveries and insights that the application of molecular biology has produced. Lecture Notes on Molecular Medicine will appeal to a wide ranging audience, from medical students to higher examination candidates, who want a straightforward introduction to one of the most important growth areas in modern medicine.